免 疫 原：KLH conjugated synthetic peptide derived from human CEBP Beta
抗原表位：21-120/345
SWISS：P17676
Gene ID ：1051
Human Gene ID：1051

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq].
Function：Involved in interleukin-6 signal transduction, including the transcriptional activation of acute-phase genes. Functions in brown adipose tissue (BAT) differentiation.
Subunit：Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and gamma. Interacts with TRIM28 and PTGES2. Interacts with PRDM16. Interacts with CCDC85B.
Subcellular Location：Nucleus.
Post-translational modifications：Sumoylated by polymeric chains of SUMO2 or SUMO3.
Similarity：Belongs to the bZIP family. C/EBP subfamily.
Contains 1 bZIP domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.