Rabbit Anti-HSL/LIPE antibody |
反应物种(预测) |
Human,Mouse,Pig,Cow,Sheep |
产品应用(已验证) |
IHC |
推荐稀释比例 |
IHC-P=1:400-800, |
研究领域 |
心血管,免疫学,生长因子和激素,糖尿病, |
标签 |
Array |
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Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSL) Polyclonal Antibody, Unconjugated (bs-22905R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
RRID:RRID
产品名称:Rabbit Anti-HSL/LIPE antibody
别名: Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN.
中文名称:荷尔蒙敏感脂肪酶抗体
英文名称:Rabbit Anti-HSL/LIPE antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆,细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human HSL/LIPE
抗原表位:441-540/1076
SWISS:Q05469
Gene ID :3991
Human Gene ID:3991
HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.
Function:In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
Subunit:Interacts with PTRF in the adipocyte cytoplasm.
Subcellular Location:Cell membrane. Membrane, caveola. Cytoplasm, cytosol.
Similarity:Belongs to the 'GDXG' lipolytic enzyme family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.