Rabbit Anti-DDX4 antibody |
反应物种(预测) |
Human,Rat,Dog,Pig,Cow,Rabbit |
产品应用(已验证) |
WB |
推荐稀释比例 |
WB=1:500-2000, |
研究领域 |
细胞生物,免疫学 |
标签 |
Array |
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Sample:
Lane 1: Testis (Mouse) Tissue Lysate at 40 ug
Primary: Anti-DDX4 (bs-22892R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 80 kD
Observed band size: 80 kD
RRID:RRID
产品名称:Rabbit Anti-DDX4 antibody
别名: DDX 4; DEAD (Asp Glu Ala Asp) box polypeptide 4; Dead box protein 4; Dead-box protein 4; MGC111074; MVH; Probable ATP dependent RNA helicase DDX4; VASA; VASA homolog; DDX4_HUMAN.
中文名称:DDX4抗体
英文名称:Rabbit Anti-DDX4 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human bs-22891R
抗原表位:591-690/724
SWISS:Q9NQI0
Gene ID :54514
Human Gene ID:54514
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function:May play a role in germ cell development. May play a role in sperm motility.
Subunit:Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. N-terminus interacts with RANBP9. Interacts with PIWIL2 and MAEL.
Subcellular Location:Cytoplasm. Cytoplasm, perinuclear region.
Tissue Specificity:Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes.
Similarity:Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.