Rabbit Anti-PAX7 antibody,蛋白Marker-蛋白检测试剂盒-IVD原料-北京博奥森生物技术有限公司

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Rabbit Anti-PAX7 antibody

多克隆 | SKU：bs-22741R

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货号:bs-3351R

￥1280

50μg

RMB1280

100μg

RMB1980

200μg

RMB2980

支持数据
产品信息
免疫原信息
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订购号:bs-22741R

￥1098.00-2900.00

50ul

100ul

200ul

货期：现货

售后保障

Rabbit Anti-PAX7 antibody
反应物种（预测）	Human,Chicken,Pig,Cow,Horse,Rabbit,Sheep
产品应用（已验证）	WB,IHC
推荐稀释比例	WB=1:500-2000,IHC-P=1:100-500,
研究领域	信号转导,转录调节因子
标签	Array

Paraformaldehyde-fixed, paraffin embedded (mouse uterus); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAX7) Polyclonal Antibody, Unconjugated (bs-22741R) at 1:2000 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse embryo); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAX7) Polyclonal Antibody, Unconjugated (bs-22741R) at 1:2000 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Sample:
Uterus(Mouse) Lysate at 40 ug
Skeletal muscle(Rat) Lysate at 40 ug
Skeletal muscle(Mouse) Lysate at 40 ug
Primary: Anti-PAX7 (bs-22741R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD

产品信息

RRID：RRID
产品名称：Rabbit Anti-PAX7 antibody
别名： Paired box gene 7; FLJ37460; HUP1; OTTHUMP00000002534; Paired box 7; Paired box homeotic gene 7; Paired box protein Pax-7; Paired domain gene 7; Paired domain gene HuP1; PAX7 transcriptional factor; PAX7/FKHR fusion gene, included; PAX7B; RGD1564360; PAX7
中文名称：配对盒基因7抗体
英文名称：Rabbit Anti-PAX7 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞核
性状：Liquid
亚型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

免疫原信息

免疫原：KLH conjugated synthetic peptide derived from human PAX7
抗原表位：141-240/520
SWISS：P23759
Gene ID ：5081
Human Gene ID：5081

产品介绍

PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of PAX7 is unknown but it is speculated to be involved in tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Function：Probable transcription factor. May have a role in myogenesis.
Subunit：Can bind to DNA as a heterodimer with PAX3. Interacts with DAXX.
Subcellular Location：Nucleus.
DISEASE：Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines.
Similarity：Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain.
Contains 1 paired domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.