免 疫 原：KLH conjugated synthetic peptide derived from human alpha Sarcoglycan
抗原表位：211-310/387
抗原细胞定位：Extracellular
SWISS：Q16586
Gene ID ：6442
Human Gene ID：6442

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Function：Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subunit：Interacts with the syntrophin SNTA1. Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated wi
Subcellular Location：Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
Tissue Specificity：Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
DISEASE：Defects in SGCA are the cause of limb-girdle muscular dystrophy type 2D (LGMD2D) [MIM:608099]; also known as Duchenne-like muscular dystrophy autosomal recessive type 2 or severe childhood autosomal recessive muscular dystrophy (SCARMD). LGMD2D is an auto
Similarity：Belongs to the sarcoglycan alpha/epsilon family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.