Rabbit Anti-GASC1/KDM4C antibody |
反应物种(预测) |
Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit |
产品应用(已验证) |
WB |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:500-5000, |
研究领域 |
肿瘤,免疫学,染色质和核信号 |
标签 |
Array |
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Sample:
A431 (Human) Cell Lysate at 30 ug
HepG2 (Human) Cell Lysate at 30 ug
Hela (Human) Cell Lysate at 30 ug
HL60 (Human) Cell Lysate at 30 ug
Primary: Anti- GASC1/KDM4C (bs-22322R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 100/120 kD
Observed band size: 120 kD
RRID:RRID
产品名称:Rabbit Anti-GASC1/KDM4C antibody
别名: GASC 1 protein; GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain containing histone demethylation protein 3C; Jumonji domain containing protein 2C; KDM4C_HUMAN.
中文名称:鳞状细胞癌增强蛋白1抗体
英文名称:Rabbit Anti-GASC1/KDM4C antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞核
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human GASC1/KDM4C
抗原表位:291-390/1056
SWISS:Q9H3R0
Gene ID :23081
Human Gene ID:23081
KDM4C/JMJD2C, a jumonji domain containing protein, is a histone demethylase. JMJD2C specifically demethylates Lysine 9 and Lysine 36 residues of Histone H3, thereby playing a central role in regulating histone modifications.
Function:Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and
Subcellular Location:Nucleus.
Tissue Specificity:Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Similarity:Belongs to the JHDM3 histone demethylase family.
Contains 1 JmjC domain.
Contains 1 JmjN domain.
Contains 2 PHD-type zinc fingers.
Contains 2 Tudor domains.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.