| Rabbit Anti-n-Myc antibody |
| 反应物种（预测） |
Rat |
| 产品应用（已验证） |
WB |
| 推荐稀释比例 |
WB=1:500-2000, |
| 研究领域 |
肿瘤,细胞生物,免疫学,染色质和核信号 |
| 标签 |
Array |
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Sample:
Lane 1: Human SH-SY5Y cell Lysates
Lane 2: Human Hela cell Lysates
Primary: Anti-n-Myc (bs-22205R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49kDa
Observed band size: 60kDa
-
Sample:
Heart (Mouse) Lysate at 40 ug
Primary: Anti-n-Myc (bs-22205R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 49 kD
RRID：RRID
产品名称：Rabbit Anti-n-Myc antibody
别名： bHLHe37; Class E basic helix-loop-helix protein 37; MODED; MYCN; MYCN_HUMAN; N myc; N myc proto oncogene protein; N-myc proto-oncogene protein; Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene; Neuroblastoma MYC oncogene; NMYC; NM
中文名称：致癌基因n-Myc抗体
英文名称：Rabbit Anti-n-Myc antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞核
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human n-Myc
抗原表位：1-100/464
SWISS：P04198
Gene ID ：4613
Human Gene ID：4613
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].
Function：May function as a transcription factor.
Subunit：Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an heterodimer with MAX. Interacts with KDM5A, KDM5B and HUWE1.
Subcellular Location：Nucleus.
DISEASE：Note=Amplification of the N-MYC gene is associated with a variety of human tumors, most frequently neuroblastoma, where the level of amplification appears to increase as the tumor progresses.
Similarity：Contains 1 basic helix-loop-helix (bHLH) domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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