免 疫 原：KLH conjugated synthetic peptide derived from human SEC62
抗原表位：251-350/399
SWISS：Q99442
Gene ID ：7095
Human Gene ID：7095

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Function：Required for preprotein translocation.
Subunit：Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.
Subcellular Location：Endoplasmic reticulum membrane.
Similarity：Belongs to the SEC62 family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.