免 疫 原：KLH conjugated synthetic peptide derived from human SNX10
抗原表位：11-100/201
SWISS：Q9Y5X0
Gene ID ：29887
Human Gene ID：29887

Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX10 (Sorting nexin-10) is a 201 amino acid protein that contains one phox domain and belongs to the SNX family. Like other members of the SNX family, SNX10 is thought to play a role in intracellular trafficking events throughout the cell.
Function：May be involved in several stages of intracellular trafficking (By similarity). May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles.
Subcellular Location：Cytoplasm. Endosome membrane.
Similarity：Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.