| Rabbit Anti-GAK protein antibody |
| 反应物种（预测） |
Human,Rat,Chicken,Dog,Cow,Horse |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
IHC,IF,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
| 研究领域 |
细胞生物,神经生物学,信号转导,细胞周期蛋白,激酶和磷酸酶 |
| 标签 |
Array |
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Sample:
Cerebrum (Mouse) Lysate at 40 ug
Large intestine (Mouse) Lysate at 40 ug
Liver (Mouse) Lysate at 40 ug
Primary: Anti- GAK protein (bs-7912R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kD
Observed band size: 25 kD
RRID：RRID
产品名称：Rabbit Anti-GAK protein antibody
别名： Cyclin G associated kinase; Cyclin-G-associated kinase; EC 2.7.11.1;
FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654.
中文名称：细胞周期蛋白G相关激酶抗体
英文名称：Rabbit Anti-GAK protein antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆,细胞膜
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human GAK protein
抗原表位：244-330/1311
SWISS：O14976
Gene ID ：2580
Human Gene ID：2580
Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Tissue specificity: Ubiquitous. Highest in testis.
Function：Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Subcellular Location：Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion (Probable). Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions.
Tissue Specificity：Ubiquitous. Highest in testis.
Similarity：Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 C2 tensin-type domain.
Contains 1 J domain.
Contains 1 phosphatase tensin-type domain.
Contains 1 protein kinase domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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