Rabbit Anti-MARVELD1 antibody |
反应物种(预测) |
Human,Rabbit |
产品应用(已验证) |
WB |
产品应用(可尝试) |
IHC,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
研究领域 |
肿瘤,肿瘤细胞生物标志物, |
标签 |
Array |
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Sample:
Cerebrum (Mouse) Lysate at 40 ug
Cerebellum (Mouse) Lysate at 40 ug
Primary: Anti- MARVELD1 (bs-6548R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 19 kD
Observed band size: 19 kD
RRID:AB_11076990
产品名称:Rabbit Anti-MARVELD1 antibody
别名: GB14; MARVD1; MARVEL (membrane-associating) domain containing 1; MARVEL domain containing protein 1; MRVLDC1; Putative MARVEL domain containing protein 1; MALD1_HUMAN.
中文名称:候选肿瘤抑制基因MARVELD1抗体
英文名称:Rabbit Anti-MARVELD1 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞核,细胞浆,细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human MARVELD1
抗原表位:31-130/173
抗原细胞定位:Extracellular
SWISS:Q9BSK0
Gene ID :83742
Human Gene ID:83742
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
Function:Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration
Subcellular Location:Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 t
Tissue Specificity:Widely expressed in normal tissues. Down-regulated in multiple primary tumors.
Similarity:Contains 1 MARVEL domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.