免 疫 原：KLH conjugated synthetic peptide derived from human DLL4
抗原表位：551-650/685
SWISS：Q9NR61
Gene ID ：54567
Human Gene ID：54567

DeltaD is one of the 4 members of the zebrafish Delta family of Notch ligands, important in the control of cell differentiation in many tissues. DeltaD acts as a ligand for Notch receptors and is involved in primary neurogenesis and somitogenesis. It can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. It is required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.
Function：Cell surface proteoglycan that bears heparan sulfate. Required for cell division patterning during post-embryonic development of the nervous system.
Subcellular Location：Cell membrane.
Similarity：Belongs to the glypican family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.