免 疫 原：KLH conjugated synthetic peptide derived from human SLC29A4
抗原表位：401-500/530
SWISS：Q7RTT9
Gene ID ：222962
Human Gene ID：222962

This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008].
Function：Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May pl
Subcellular Location：Cell membrane; Multi-pass membrane protein (Potential). Apical cell membrane; Multi-pass membrane protein (Potential). Note=Located to the plasma membranes of ventricular myocytes and vascular endothelial cells. Targeted to the apical membranes of differe
Tissue Specificity：Expressed abundantly in the heart, in both cardiomyocytes and vascular endothelial cells (at protein level). Highly expressed in brain, kidney and skeletal muscle. In the brain expressed in cerebellum, cerebral cortex, medulla, occipital pole, frontal and
Post-translational modifications：N-glycosylated.
Similarity：Belongs to the SLC29A transporter family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.