Rabbit Anti-IDH3A antibody |
反应物种(预测) |
Mouse,Rat,Pig,Cow,Horse,Rabbit |
产品应用(已验证) |
WB,ICC |
产品应用(可尝试) |
IHC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
研究领域 |
肿瘤,细胞生物,免疫学,染色质和核信号,信号转导,转录调节因子,激酶和磷酸酶 |
标签 |
Array |
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Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- IDH3A (bs-3946R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
RRID:AB_10856637
产品名称:Rabbit Anti-IDH3A antibody
别名: EC 1.1.1.41; H IDH alpha; HIDH alpha; Isocitrate dehydrogenase (NAD+) alpha chain precursor; Isocitrate dehydrogenase [NAD] subunit alpha mitochondrial; Isocitrate dehydrogenase 3 (NAD+) alpha; Isocitrate dehydrogenase; Isocitric dehydrogenase; NAD; NAD(H
中文名称:草酰琥珀酸脱羧酶α抗体
英文名称:Rabbit Anti-IDH3A antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human IDH3A
抗原表位:281-366/366
SWISS:P50213
Gene ID :3419
Human Gene ID:3419
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Subunit:Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.
Subcellular Location:Mitochondrion.
Similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.