| Rabbit Anti-IL18R Beta antibody |
| 反应物种（预测） |
Human,Rat,Dog,Horse |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
| 研究领域 |
细胞生物,免疫学 |
| 标签 |
Array |
-
Sample:Spleen (Mouse)Lysate at 40 ug
Primary: Anti-IL18R Beta(bs-2616R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 68kD
Observed band size: 68kD
-
Sample:
Lane 1: Human U937 cell lysates
Lane 2: Human HL60 cell lysates
Lane 3: Human A549 cell lysates
Lane 4: Human Du145 cell lysates
Primary: Anti- IL18R Beta (bs-2616R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 66 kD
RRID：AB_10856465
产品名称：Rabbit Anti-IL18R Beta antibody
别名： IL-18R Beta; Interleukin-18 receptor beta; Accessory protein like; IL18R Beta; AcPL; IL 18RacP; IL 1R accessor protein like; IL 1R7; IL 1RacPL; IL18Rbeta; Interleukin 18 receptor accessory protein; IL18RAP; Interleukin-18 receptor accessory protein-like;
中文名称：白细胞介素-18受体β链抗体
英文名称：Rabbit Anti-IL18R Beta antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞膜
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human IL-18R beta
抗原表位：15-120/599
抗原细胞定位：Extracellular
SWISS：O95256
Gene ID ：8807
Human Gene ID：8807
IL18R Beta is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and IL18R Beta is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
Function：Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex. Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
Subunit：Together with IL18R1, probably belongs to the IL-18 receptor complex. Seems not to interact directly with IL-18.
Subcellular Location：Membrane; Single-pass type I membrane protein.
Tissue Specificity：Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
Similarity：Belongs to the interleukin-1 receptor family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
说明书
联系我们
打印此页面
收藏