| Rabbit Anti-BRD2 antibody |
| 反应物种（预测） |
Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
IHC,ICC,IF,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
| 研究领域 |
信号转导,激酶和磷酸酶,表观遗传学, |
| 标签 |
Array |
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Sample:
Lane 1: Molt-4 (Human) Cell Lysate at 30 ug
Lane 2: MDA-MB-231 (Human) Cell Lysate at 30 ug
Primary: Anti-BRD2 (bs-12888R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 110-115 kD
Observed band size: 130 kD
RRID：RRID
产品名称：Rabbit Anti-BRD2 antibody
别名： Bromodomain-containing protein 2; KIAA9001; RING3; O27.1.1; Really interesting new gene 3 protein; BRD2_HUMAN;
中文名称：BRD2蛋白抗体
英文名称：Rabbit Anti-BRD2 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞核
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human BRD2
抗原表位：301-400/801
SWISS：P25440
Gene ID ：6046
Human Gene ID：6046
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Function：May play a role in spermatogenesis or folliculogenesis.
Subunit：Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.
Subcellular Location：Nucleus.
Similarity：Contains 2 bromo domains.
Contains 1 ET domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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