免 疫 原：KLH conjugated synthetic peptide derived from human RBP4
抗原表位：71-170/201
SWISS：P02753
Gene ID ：5950
Human Gene ID：5950

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008].
Function：Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
Subcellular Location：Secreted.
DISEASE：Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Similarity：Belongs to the calycin superfamily. Lipocalin family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.