Rabbit Anti-Mitoferrin 2/SLC25A28 antibody |
反应物种(预测) |
Human,Dog,Pig,Cow,Sheep |
产品应用(已验证) |
WB |
产品应用(可尝试) |
IHC,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
研究领域 |
肿瘤,细胞生物,神经生物学,信号转导,新陈代谢,线抗体, |
标签 |
Array |
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Sample:
Lane 1: Liver (Mouse) Lysate at 40 ug
Lane 2: Liver (Rat) Lysate at 40 ug
Lane 3: Heart (Rat) Lysate at 40 ug
Primary:
Anti-Mitoferrin 2/SLC25A28 (bs-7157R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kD
Observed band size: 37 kD
RRID:RRID
产品名称:Rabbit Anti-Mitoferrin 2/SLC25A28 antibody
别名: MFRN2; Mitochondrial iron transporter 2; Mitochondrial RNA splicing protein 3/4; Mitoferrin 2; Mitoferrin2; Mitoferrin-2; MRS3/4; MRS4L; NPD016; Putative mitochondrial solute carrier; MFRN2_HUMAN; SLC25A28.
中文名称:线粒体铁转运蛋白2抗体
英文名称:Rabbit Anti-Mitoferrin 2/SLC25A28 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human Mitoferrin 2
抗原表位:271-364/364
SWISS:Q96A46
Gene ID :81894
Human Gene ID:81894
Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Function:SLC25A28 is a mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells.
Subcellular Location:Mitochondrion inner membrane; Multi pass membrane protein. Note: Isoform 1 and isoform 2 are both localized in the mitochondrion.
Tissue Specificity:Ubiquitous. Expressed in placenta, lung, kidney, pancreas, liver, brain, skeletal muscle and heart.
Similarity:Belongs to the mitochondrial carrier (TC 2.A.29) family.
Contains 3 Solcar repeats.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.