货号 |
bs-1955R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-MCP1 antibody |
中文名称 |
Rabbit Anti-MCP1 antibody |
研究领域 |
肿瘤,细胞生物,免疫学,细胞凋亡,生长因子和激素,转录调节因子 |
英文别名 |
MCP-1/CCL2; C-C motif chemokine 2;
CCL 2;
CCL2;
CCL2_HUMAN;
Chemokine (C C motif) ligand 2;
Chemokine C C motif ligand 2;
Chemokine CC Motif Ligand 2;
GDCF 2;
GDCF 2 HC11;
GDCF-2;
GDCF2;
HC11;
HSMCR30;
HSMCR30;
JE;
MCAF;
MCP 1;
MCP-1;
MG |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse,Dog,Pig,Horse,Rabbit |
产品应用(已验证) |
IHC,FCM |
产品应用(可推荐) |
WB,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1ug/Test,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
11 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human MCP-1 |
抗原表位 |
24-99/99 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
SIMILARITY |
Belongs to the intercrine beta (chemokine CC) family. |
SUBUNIT |
Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. |
Function |
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arth |
Post-translational |
Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. |
SWISS |
P13500 |
Gene ID |
6347 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside. |