货号 |
bs-24598R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Myozenin 1 antibody |
中文名称 |
Rabbit Anti-Myozenin 1 antibody |
研究领域 |
心血管,细胞生物,信号转导 |
英文别名 |
MYOZ1; Myozenin; myozenin 1; Myozenin-1; Calsarcin-2; Filamin, actinin and telethonin binding protein; actinin- and telethonin-binding protein; MYOZ1_MOUSE; Protein FATZ; CS 2; FATZ; Protein FATZ; Calsarcin 2. |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:400-800, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
31 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Myozenin 1 |
抗原表位 |
1-100/299 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle. |
Tissue |
Expressed primarily in skeletal muscle and specifically enriched in the gastrocnemius, which is composed predominantly of fast-twitch muscle fibers. Detected at lower levels in heart. |
SIMILARITY |
Belongs to the myozenin family. |
SUBUNIT |
Interacts with ACTN2, ACTN3, FLNA, FLNB, FLNC, LDB3, PPP3CA and TCAP. Interacts via its C-terminal region with MYOT. |
Function |
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of |
SWISS |
Q9JK37 |
Gene ID |
59011 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. MYOZ (Myozenin 1) plays an important role in the modulation of calcineurin signaling. MYOZ1 may play a role in myofibrillogenesis. MYOZ1 interacts with ACTN2, ACTN3, FLNA, FLNB, FLNC, LDB3, PPP3CA and TCAP and interacts via its C-terminal region with MYOT. MYOZ1 is localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. MYOZ1 colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle. MYOZ1 is expressed primarily in skeletal muscle and specifically enriched in the gastrocnemius, which is composed predominantly of fast-twitch muscle fibers. |