货号 |
bsm-52533R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Mast Cell Tryptase antibody |
中文名称 |
Rabbit Anti-Mast Cell Tryptase antibody |
产品标签 |
重组兔单抗 |
研究领域 |
细胞生物,免疫学,激酶和磷酸酶 |
英文别名 |
Tryptase delta; Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3; TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE; EC 3.4.21.59; MGC95428; TRYD; Tryptase3; alpha II; EC 3.4.21.59; Lung tryptase; Mast cell alpha II tryptase; Mast cell beta I |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse,Rat |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IP |
推荐稀释比例 |
WB=1:500-2000,IP=1:10-50,IHC-P=1:50-200,IHC-F=1:50-200, |
克隆类型 |
单克隆 |
克隆号 |
3G3 |
抗体来源 |
Rabbit |
理论分子量 |
23 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
Recombinant human Mast Cell Tryptase |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. Note=Released from the secretory granules upon mast cell activation. |
Tissue |
Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. |
SIMILARITY |
Belongs to the peptidase S1 family. Tryptase subfamily.
Contains 1 peptidase S1 domain. |
SUBUNIT |
Homotetramer. |
Function |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. |
SWISS |
Q15661 |
Gene ID |
7177 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] |