货号 |
bs-22905R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-HSL/LIPE antibody |
中文名称 |
Rabbit Anti-HSL/LIPE antibody |
研究领域 |
心血管,免疫学,生长因子和激素,糖尿病, |
英文别名 |
Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN. |
反应物种(已验证) |
Rat |
反应物种(预测) |
Human,Mouse,Pig,Cow,Sheep |
产品应用(已验证) |
IHC |
推荐稀释比例 |
IHC-P=1:400-800, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
116 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human HSL/LIPE |
抗原表位 |
441-540/1076 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. |
SIMILARITY |
Belongs to the 'GDXG' lipolytic enzyme family. |
SUBUNIT |
Interacts with PTRF in the adipocyte cytoplasm. |
Function |
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. |
SWISS |
Q05469 |
Gene ID |
3991 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. |