货号 |
bs-22743R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-KGF antibody |
中文名称 |
Rabbit Anti-KGF antibody |
研究领域 |
肿瘤,免疫学,信号转导,生长因子和激素 |
英文别名 |
FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7;HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding growth factor 7. |
反应物种(已验证) |
Mouse,Rat |
反应物种(预测) |
Human,Dog,Pig,Cow,Horse,Rabbit |
产品应用(已验证) |
WB |
推荐稀释比例 |
WB=1:500-2000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
18 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human KGF |
抗原表位 |
32-110/194 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
Tissue |
Epithelial cell. |
SIMILARITY |
Belongs to the heparin-binding growth factors family. |
SUBUNIT |
Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. |
Function |
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cel |
SWISS |
P21781 |
Gene ID |
2252 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. |