货号 |
bs-22346R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-GDNFRA antibody |
中文名称 |
Rabbit Anti-GDNFRA antibody |
研究领域 |
免疫学,神经生物学 |
英文别名 |
GDNF Receptor alpha 1; GFRa-1; GFR alpha; GDNFR alpha; TmR1; GFR alpha-1; RETL1; RET ligand 1; TGF-beta related neurotrophic factor receptor-1; AU042498; DKFZp313E1012; DKFZp686J0156; FLJ10561; FLJ31546; GDNFR; Gdnfr alpha; GFR-ALPHA-1; GFRA1; GRFA1; LOC1 |
中文别名 |
TGF-β related neurotrophic factor receptor-1; |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Chicken,Dog,Pig,Cow,Rabbit |
产品应用(已验证) |
WB |
推荐稀释比例 |
WB=1:500-2000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
44 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human GDNFRA |
抗原表位 |
81-180/465 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane; Lipid-anchor, GPI-anchor. |
SIMILARITY |
Belongs to the GDNFR family. |
SUBUNIT |
2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET. |
Function |
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. |
SWISS |
P56159 |
Gene ID |
2674 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] |