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货号 | bs-21617R-1 |
品牌 | |
浓度 | |
货期 | 现货 |
英文名称 | Rabbit Anti-SFTPD antibody |
中文名称 | Rabbit Anti-SFTPD antibody |
研究领域 | 肿瘤,免疫学 |
英文别名 | SFTPD surfactant protein D; pulmonary surfactant-associated glycoprotein D; COLEC 7; COLEC7; Collectin7; PSP D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; SFTP 4; SFTP4; SFTPD; SP D; Surfactant associated protein pul |
反应物种(已验证) | Human |
反应物种(预测) | Mouse,Rat |
产品应用(已验证) | WB,IHC,FCM |
产品应用(可推荐) | ICC,IF,ELISA |
推荐稀释比例 | WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=2ug/Test,IF=1:100-500,ICC=1:100-500, |
克隆类型 | 多克隆 |
抗体来源 | Rabbit |
理论分子量 | 41 |
细胞定位 | 分泌型蛋白 |
性状 | Liquid |
免疫原 | KLH conjugated synthetic peptide derived from mouse SFTPD |
抗原表位 | 301-400/374 |
亚型 | IgG |
纯化方法 | affinity purified by Protein A |
SUBCELLULAR | Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
SIMILARITY | Belongs to the SFTPD family.
Contains 1 C-type lectin domain. Contains 1 collagen-like domain. |
SUBUNIT | Oligomeric complex of 4 set of homotrimers. |
Function | Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
Post-translational | The N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates. |
SWISS | P50404 |
Gene ID | 20390 |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 | Surfactant protein D contributes to the lung's defense against inhaled microorganisms. It's a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 37-43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells. |