货号 |
bs-23071R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-HES5 antibody |
中文名称 |
Rabbit Anti-HES5 antibody |
研究领域 |
信号转导,干细胞,转录调节因子 |
英文别名 |
BHLHB38; Transcription factor HES-5; Class B basic helix-loop-helix protein 38 (bHLHb38); Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN. |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Dog,Cow,Horse |
产品应用(已验证) |
IHC,ICC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
18 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human HES5 |
抗原表位 |
31-130/166 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. |
Tissue |
Expressed in fetal heart and brain tumors. |
SIMILARITY |
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 Orange domain. |
SUBUNIT |
Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family. |
Function |
Transcriptional repressor of genes that require a bHLH protein for their transcription |
SWISS |
Q5TA89 |
Gene ID |
388585 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008] |