货号 |
bs-18727R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-MCM-BP antibody |
中文名称 |
Rabbit Anti-MCM-BP antibody |
研究领域 |
细胞生物,信号转导,表观遗传学, |
英文别名 |
C10orf119 ;
chromosome 10 open reading frame 119 ;
MCM-binding protein ;
MCM-BP ;
mcmbp ;
MCMBP_HUMAN ;
Mini-chromosome maintenance complex-binding protein ;
Minichromosome maintenance complex binding protein. |
反应物种(已验证) |
Rat |
反应物种(预测) |
Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
IHC |
推荐稀释比例 |
IHC-P=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
73 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human MCM-BP |
抗原表位 |
551-642/642 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Note: Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chro |
SIMILARITY |
Belongs to the MCMBP family. |
SUBUNIT |
Interacts with the MCM complex: associates with the MCM3-7 complex which lacks MCM2, while it does not interact with the MCM complex when MCM2 is present (MCM2-7 complex). Interacts with the RPA complex, when composed of all RPA1, RPA2 and RPA3 components |
Function |
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex |
SWISS |
Q9BTE3 |
Gene ID |
79892 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |