货号 |
bs-8267R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-GIMAP1 antibody |
中文名称 |
Rabbit Anti-GIMAP1 antibody |
研究领域 |
细胞生物,免疫学,G蛋白偶联受体,G蛋白信号, |
英文别名 |
GIMA1_HUMAN; GIMAP1; GTPase IMAP family member 1; hIMAP1; Immunity-associated protein 1. |
反应物种(已验证) |
Rat |
反应物种(预测) |
Human,Mouse,Horse,Rabbit |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
IF |
推荐稀释比例 |
IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
34 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human GIMAP1 |
抗原表位 |
31-130/306 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane (By similarity). |
Tissue |
Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. |
SIMILARITY |
Belongs to the IAN GTP-binding protein family. |
Function |
May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity). |
SWISS |
Q8WWP7 |
Gene ID |
170575 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP1 (GTPase, IMAP family member 1), also known as IMAP1 (immunity-associated protein 1), HIMAP1 or IMAP38, is a 306 amino acid single-pass type IV membrane protein of the endoplasmic reticulum (ER) belonging to the GIMAP family. Encoded by a gene located on human chromosome 7, GIMAP1 is expressed primarily in spleen with lower levels found in lymph node. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |