货号 |
bs-8711R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-DUSP27 antibody |
中文名称 |
Rabbit Anti-DUSP27 antibody |
研究领域 |
细胞生物,信号转导,激酶和磷酸酶 |
英文别名 |
Atypical dual specific protein phosphatase; Dual specificity phosphatase 27; Dual specificity phosphatase and pro isomerase domain containing 1; Dual specificity phosphatase DUPD1; dupd1; DUPD1_HUMAN; DUSP27; OTTHUMP00000019871. |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB |
推荐稀释比例 |
WB=1:500-2000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
25 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human DUSP27 |
抗原表位 |
21-120/220 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. |
Tissue |
Skeletal muscle, liver and adipose tissue. |
SIMILARITY |
elongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain. |
SUBUNIT |
Homodimer. |
SWISS |
Q68J44 |
Gene ID |
338599 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |