货号 |
bs-11573R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Neuro D antibody |
中文名称 |
Rabbit Anti-Neuro D antibody |
研究领域 |
细胞生物,神经生物学,信号转导,转录调节因子,表观遗传学, |
英文别名 |
NeuroD4; BAF45B; BRG1-associated factor 45B; D4; DPF1; DPF 1; DPF=1; DPF1_HUMAN; NEUD4; NEUD 4; Zinc and double PHD fingers family 1; Zinc finger protein neuro-d4. |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Cow,Horse,Sheep |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
WB,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
42 |
细胞定位 |
细胞核,细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Neuro D4 |
抗原表位 |
301-380/380 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. Nucleus. |
SIMILARITY |
Belongs to the requiem/DPF family.
Contains 2 PHD-type zinc fingers. |
SUBUNIT |
Component of neuron-specific chromatin remodeling complex (nBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARC |
Function |
May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a swi |
SWISS |
Q92782 |
Gene ID |
8193 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
DPF1 is a 353 amino acid protein that contains two PHD-type zinc fingers and belongs to the requiem/DPF family. Localized to both the nucleus and the cytoplasm, DPF1 is thought to play an important role in the regulation of neuronal cell survival. Specifically, DPF1 may function as a neurospecific transcription factor that binds DNA and participates in cell cycle progression. Human and rat DPF1 share 93% sequence identity, suggesting a conserved role between species. Multiple isoforms of DPF1 exist due to alternative splicing events. |