货号 |
bs-5812R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-PHLP antibody |
中文名称 |
Rabbit Anti-PHLP antibody |
研究领域 |
细胞生物,信号转导,G蛋白偶联受体,G蛋白信号, |
英文别名 |
PDCL;
Phosducin Like;
PhLP;
Phosducin-Like Protein;
PHLOP1; Phosducin like protein;
PhLP1; PHLP_HUMAN. |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Chicken,Pig,Horse,Rabbit |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
34 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human PHLP |
抗原表位 |
51-150/301 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Expressed in buccal mucosa cell and 236 other tissues |
SIMILARITY |
Belongs to the phosducin family. |
SUBUNIT |
Forms a complex with the beta and gamma subunits of the GTP-binding protein, transducin. Interacts with the CCT chaperonin complex. |
Function |
Acts as a positive regulator of hedgehog signaling and regulates ciliary function. Isoform 1:
Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 hetero |
SWISS |
Q13371 |
Gene ID |
5082 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] |