货号 |
bs-4200R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Selenium Binding Protein 1 antibody |
中文名称 |
Rabbit Anti-Selenium Binding Protein 1 antibody |
研究领域 |
肿瘤,免疫学,神经生物学,信号转导 |
英文别名 |
56 kDa selenium binding protein;
56 kDa selenium-binding protein;
hSBP;
LPSB;
SBP;
SBP1;
SBP1_HUMAN;
SBP56;
Selenbp1;
Selenbp2;
Selenium binding protein 2;
Selenium binding protein1;
Selenium-binding protein 1;
SELNBP1;
SP56. |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Cow,Rabbit |
产品应用(已验证) |
WB,IHC,FCM |
产品应用(可推荐) |
ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=2ug/Test,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
52 |
细胞定位 |
细胞核,细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1 |
抗原表位 |
401-472/472 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes. |
Tissue |
Present in liver and colon (at protein level). |
SIMILARITY |
Belongs to the selenium-binding protein family. |
SUBUNIT |
Interacts with USP33. |
Function |
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. |
Post-translational |
The N-terminus is blocked. |
SWISS |
Q13228 |
Gene ID |
8991 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease. |