货号 |
bs-1717R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Cytokeratin 13 antibody |
中文名称 |
Rabbit Anti-Cytokeratin 13 antibody |
研究领域 |
肿瘤 |
英文别名 |
type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin-13; K13; K1C13_HUMAN; Ka13; Keratin 13; Keratin; keratin type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; MGC161462; MGC3781; Type I keratin Ka13; Keratin, type I cytoskelet |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Dog,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
49 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Cytokeratin-13 |
抗原表位 |
251-350/458 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) . WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spo |
SIMILARITY |
Belongs to the intermediate filament family. |
SUBUNIT |
Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4. |
DISEASE |
White sponge nevus of cannon (WSN) [MIM:193900]: Rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucos |
SWISS |
P13646 |
Gene ID |
3860 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008]. |