货号 |
bs-12706R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-B4GALNT1/GM2 synthase antibody |
中文名称 |
Rabbit Anti-B4GALNT1/GM2 synthase antibody |
研究领域 |
细胞生物,神经生物学,信号转导,转录调节因子,新陈代谢, |
英文别名 |
(N acetylneuraminyl) galactosylglucosylceramide;
(N-acetylneuraminyl)-galactosylglucosylceramide;
4 N-acetylgalactosaminyltransferase 1;
4933429D13Rik;
B4GALNT1;
B4GN1_HUMAN;
Beta 1 4 N acetyl galactosaminyl transferase 1;
Beta 1 4 N acetylgalactos |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
59 |
细胞定位 |
细胞浆,细胞膜,细胞外基质 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human B4GALNT1/GM2 synthase |
抗原表位 |
451-533/533 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Golgi apparatus membrane; Single-pass type II membrane protein. |
SIMILARITY |
Belongs to the glycosyltransferase 2 family. |
SUBUNIT |
Homodimer; disulfide-linked. |
Function |
Involved in the biosynthesis of gangliosides GM2, GD2 and GA2. |
DISEASE |
Spastic paraplegia 26, autosomal recessive (SPG26) [MIM:609195]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of s |
SWISS |
Q00973 |
Gene ID |
2583 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |