货号 |
bs-5159R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-MYLPF antibody |
中文名称 |
Rabbit Anti-MYLPF antibody |
研究领域 |
免疫学,信号转导,细胞骨架,细胞外基质, |
英文别名 |
2410014J02Rik;
DKFZp779C0757;
DTNB;
Fast skeletal myosin light chain 2;
G2;
HUMMLC2B;
MGC13450;
MLC 2; MRLC2; MYL11;
MLC2B;
MLC2F;
MLRS_HUMAN;
MYLPF;
Myosin light polypeptide 2 alkali;
Myosin regulatory light chain 2, skeletal muscle isoform. |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
19 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Fast skeletal myosin light chain 2 |
抗原表位 |
101-170/170 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Expressed in fetal and adult skeletal muscle. |
SIMILARITY |
Contains 3 EF-hand domains. |
SUBUNIT |
Myosin is a hexamer of 2 heavy chains and 4 light chains. |
SWISS |
Q96A32 |
Gene ID |
29895 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins . Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle. |