货号 |
bs-1963R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-KLK1 antibody |
中文名称 |
Rabbit Anti-KLK1 antibody |
研究领域 |
肿瘤,细胞生物,信号转导,激酶和磷酸酶 |
英文别名 |
Kallikrein 1; Kallikrein-1; hK1; Klk6; KLKR; Glandular kallikrein 1; hK 1; Kallikrein serine protease 1; Kidney/pancreas/salivary gland kallikrein; Klk 6; Tissue kallikrein; Klk1b3; Klk1c1; Ngfg; rGK-1; preprokallikrein; KLK1_HUMAN. |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Horse,Rabbit |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
26 |
细胞定位 |
细胞核,分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human KLK1 |
抗原表位 |
101-200/262 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84. |
SIMILARITY |
Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. |
Function |
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. |
Post-translational |
The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located. |
SWISS |
P06870 |
Gene ID |
3816 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008] |