货号 |
bs-10296R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Claudin 5 antibody |
中文名称 |
Rabbit Anti-Claudin 5 antibody |
研究领域 |
信号转导,细胞粘附分子,细胞骨架, |
英文别名 |
AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); Claudin5; Claudin-5;CLDN 5; CLDN5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofac |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB,FCM |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,Flow Cyt=2ug/Test, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
23 |
细胞定位 |
细胞膜,细胞外基质 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Claudin 5 |
抗原表位 |
29-81/218 |
抗原细胞定位 |
Extracellular |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
Tissue |
Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. |
SIMILARITY |
Belongs to the claudin family. |
SUBUNIT |
Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ. |
Function |
Plays a major role in tight junction-specific obliteration of the intercellular space. |
SWISS |
O00501 |
Gene ID |
7122 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008] |