货号 |
bs-2801R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-SMO antibody |
中文名称 |
Rabbit Anti-SMO antibody |
研究领域 |
肿瘤,免疫学,信号转导,细胞膜受体 |
英文别名 |
Gx; Gx protein; Smoothened; SMOH; Smoothened homolog (Drosophila); Smoothened homolog; Smoothened homolog precursor (SMO) (Gx protein); SMO_HUMAN. |
反应物种(已验证) |
Mouse |
反应物种(预测) |
Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit |
产品应用(可推荐) |
WB,IHC,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
84 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human SMO |
抗原表位 |
551-650/787 |
抗原细胞定位 |
Cytoplasmic |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Membrane. |
SIMILARITY |
Belongs to the G-protein coupled receptor Fz/Smo family. Contains 1 FZ (frizzled) domain. |
SUBUNIT |
Interacts with ARRB2. Interacts with KIF7. |
Function |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO) |
SWISS |
Q99835 |
Gene ID |
6608 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] |